Nature Podcast

Springer Nature Limited

The Nature Podcast brings you the best stories from the world of science each week. We cover everything from astronomy to zoology, highlighting the most exciting research from each issue of the Nature journal. We meet the scientists behind the results and provide in-depth analysis from Nature's journalists and editors.

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Categories: Science & Medicine

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00:46 Using genomics to explain geographic differences in cancer risk

The risk of developing cancer can vary hugely depending on geographic region, but it’s not exactly clear why. To get a better idea, a team has compared the genomes of kidney cancers taken from people around the globe. They reveal a link between geographical locations and specific genetic mutations, suggesting that there are as-yet unknown environmental or chemical exposures in different locations. They hope this work will inform public health efforts to identify and reduce potential causes of cancer.

Research Article: Senkin et al.

News and Views: Genomics reveal unknown mutation-promoting agents at global sites

07:46 Research Highlights

Research reveals that the extinct ‘sabre-toothed salmon’ actually had tusks, and a common fungus that can clean up both heavy-metal and organic pollutants.

Research Highlight: This giant extinct salmon had tusks like a warthog

Research Highlight: Garden-variety fungus is an expert at environmental clean-ups

09:55 How disrupting a male mouse’s microbiome affects its offspring

Disruption of the gut microbiota has been linked to issues with multiple organs. Now a team show disruption can even affect offspring. Male mice given antibiotics targeting gut microbes showed changes to their testes and sperm, which lead to their offspring having a higher probability of severe growth issues and premature death. Although it’s unknown whether a similar effect would be seen in humans, it suggests that factors other than genetics play a role in intergenerational disease susceptibility.

Research article: Argaw-Denboba et al.

News and Views: Dad’s gut microbes matter for pregnancy health and baby’s growth